Research Article

Value of Liver Regeneration in Predicting Short-Term Prognosis for Patients with Hepatitis B-Related Acute-on-Chronic Liver Failure

Table 1

Clinical characteristics and outcomes of HBV-ACLF patients.

Training cohort ()Testing cohort ()

Age (years)0.825
Gender (male, %)174 (84.47%)82 (80.39%)0.369
TBil (μmol/L)252.55 (86.50, 795.70)281.86 (86.61, 1004.50)0.528
Cre (μmol/L)73.70 (31.00, 505.00)74.30 (43.00, 371.00)0.793
Alb (g/L)0.428
Leukocyte count (×109/L)6.60 (1.80, 37.50)6.42 (2.16, 21.60)0.997
Neutrophil count (×109/L)4.31 (0.64, 33.38)4.54 (0.86, 16.83)0.778
ALT (IU/L)365.85 (21.80, 5124.20)302.00 (16.20, 6189.40)0.988
AST (IU/L)302.25 (40.50, 7025.20)318.35 (49.90, 3562.70)0.883
INR1.95 (1.50, 7.26)1.91 (1.50, 6.96)0.440
AFP (ng/mL)52.75 (1.04, 3858.00)35.87 (0.83, 1495.82)0.740
HBeAg positive (%)47 (22.82%)29 (28.43%)0.282
HBV DNA (log10 IU/mL)5.07 (2.01, 9.76)5.49 (2.30, 9.81)0.298
HE (%)109 (52.91%)55 (53.92%)0.867
Ascites (%)142 (68.93%)79 (77.45%)0.118
28-day mortality (%)67 (32.52%)32 (31.37%)0.839
90-day mortality (%)86 (41.75%)42 (41.18%)0.924

AFP: alpha-fetoprotein; Alb: albumin; ALT: alanine aminotransferase; AST: aspartate aminotransferase; Cre: creatine; HE: hepatic encephalopathy; INR: international normalized ratio; TBil: total bilirubin.