Research Article

A System Biology-Based Approach for Designing Combination Therapy in Cancer Precision Medicine

Figure 10

Physical structure of the ABSM as a square lattice. (a) The considered tumor is composed of three layers: necrotic cells (dark grey layer), quiescent cells (middle shaded layer), and proliferating cells (dotted layer). The average radius of the tumor, necrotic layer, and the average thickness of the outer proliferating cancerous cells layer are shown by t, n, and p, respectively. (b) The Moore neighbors (grey cells) of the central (checker background) cell.
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