A System Biology-Based Approach for Designing Combination Therapy in Cancer Precision Medicine

Table 12

Introduction of agents of ABSM and their states.

Agent	Description	Possible states	Symbol
NA	Nonimmune cells	0—normal cell or empty space (N)	NA_0
		1—proliferating tumor cell (PT)	NA_1
		2—nonproliferating tumor cell or quiescent cell (NT)	NA_2
		3—necrotic cell (Ne)	NA_3
IA	Immune cells	0—natural killer cell	IA_0
		1—cytotoxic T lymphocyte (CTL)	IA_1