A System Biology-Based Approach for Designing Combination Therapy in Cancer Precision Medicine

Table 14

The typical value of ABSM parameters used in simulations.

Parameter	Brief explanation	Value
	Base probability of division of NA_1_1 cell	0.7
	Base probability of division of NA_1_2 cell	0.6
	Base necrotic thickness, controlled by nutritional needs	0.42 [30, 89]
	Base proliferative thickness, controlled by nutritional needs	0.11 [30, 89]
max	Maximum tumor extent, controlled by pressure response	37.5 mm [30, 89]
	Tumor death constant	0.5
	Immune death constant	0.2