Research on the Impact and Mechanism for the Inhibition of Micrococcus Catalase Activity by Typical Tetracyclines

Table 2

Combination area ratio and energy change for TC-CAT complexes at different combination sites.

TCs	Combination area ratio for catalytic active center	Combination area ratio for noncatalytic active center	Energy change for catalytic active center (kcal/mol)	Energy change for noncatalytic active center (kcal/mol)	Combination sites
Tetracycline	58%	53%	|-5.9784|	|-3.2641|	Catalytic active center
Chlortetracycline	62%	57%	|-7.9117|	|-4.8341|
Oxytetracycline	58%	56%	|-6.9473|	|-4.5725|
Doxycycline	55%	53%	|-3.5510|	|-3.3425|