BioMed Research International

Research Article

Hematologic Features of Children and Adolescent Patients with Acute Hypersensitivity Reactions on Drugs and Food

Table 3

Dynamics hemogram in children with acute food and drug-induced hypersensitivity reactions.


Parameters		Group of patients
Parameters		First day	After	Statistics

RBC (10¹²/l)	n = 65	4.40 [4.29; 4.50]	4.52 [4.42; 4.63]	t = −2.96,
	FH group, n = 31	4.49 [4.33; 4.65]	4.63 [4.45; 4.81]	t = −2.03,
	DH group, n = 34	4.31 [4.18; 4.45]	4.42 [4.30; 4.54]	t = −2.15,

HB (g/L)	n = 65	131.11 [128.12; 134.10]	136.19 [133.44; 138.93]	t = −4.96,
	FH group, n = 31	134.71 [129.89; 139.53]	138.35 [133.96; 142.74]	t = −2.35,
	DH group, n = 34	127.82 [124.30; 131.34]	134.21 [130.72; 137.69]	t = −4.78, = 0.00003

MCV (fl)	n = 65	81.89 [80.69; 83.09]	81.68 [80.54; 82.82]	t = 0.84,
	FH group, n = 31	81.7 [80.23; 83.17]	81.14 [79.81; 82.47]	t = 1.34,
	DH group, n = 34	82.05 [80.14; 83.95]	82.17 [80.30; 84.03]	t = 0.08,

MCH (pg)	n = 65	27.88 [27.30; 28.46]	28.20 [27.52; 28.88]	t = −1.42,
	FH group, n = 31	27.76 [27.02; 28.51]	28.13 [27.25; 29.00]	t = −1.15,
	DH group, n = 34	27.98 [27.08; 28.88]	28.27 [27.19; 29.34]	t = −0.89,

PLT (10⁹/l)	n = 65	297.18 [277.69; 316.66]	298.52 [279.48; 317.55]	t = −0.16,
	FH group, n = 31	291.83 [259.69; 323.96]	285.79 [257.13; 314.46]	t = 0.21,
	DH group, n = 36	301.88 [276.99; 326.76]	309.69 [283.48; 335.91]	t = −0.41,

MPV (fl)	n = 65	10.52 [10.22; 10.81]	10.27 [10.01; 10.54]	t = 3.35,
	FH group, n = 31	10.94 [10.54; 11.34]	10.75 [10.32; 11.18]	t = 2.07,
	DH group, n = 36	10.25 [9.90; 10.59]	9.86 [9.59; 10.12]	t = 2.72,

P-lcr (%)	n = 65	28.85 [26.64; 31.07]	27.13 [25.13; 29.12]	t = 2.41,
	FH group, n = 31	32.07 [29.02, 35.12]	30.88 [27.87; 33.89]	t = 2.04,
	DH group, n = 34	26.21 [23.50; 28.91]	23.86 [21.68, 26.04]	t = 1.49,

WBC (abs, 109/l)	n = 65	11.47 [10.42; 12.51]	10.61 [9.69; 11.52]	t = 1.51,
	FH group, n = 31	11.27 [9.67; 12.88]	10.74 [9.18; 12.29]	t = 0.61,
	DH group, n = 34	11.65 [10.20; 13.09]	10.49 [9.36; 11.61]	t = 1.55,

NEUT (abs, 10⁹/l)	n = 65	9.03 [7.94; 10.11]	5.14 [4.42; 5.86]	t = 6.09
	FH group, n = 31	9.42 [7.90; 10.94]	5.15 [4.02; 6.28]	t = 3.77,
	DH group, n = 34	8.68 [7.08; 10.29]	5.13 [4.15; 6.11]	t = 4.75,

LYM (abs, 10⁹/l)	n = 65	2.05 [1.70; 2.40]	4.05 [3.58; 4.51]	t = −7.07,
	FH group, n = 31	1.78 [1.35; 2.20]	3.83 [3.13; 4.53]	t = −5.65,
	DH group, n = 34	2.28 [1.74; 2.81]	4.23 [3.59; 4.87]	t = −4.53,

MONO (abs, 10⁹/l)	n = 65	0.46 [0.36; 0.56]	0.81 [0.73; 0.89]	t = −6.32,
	FH group, n = 31	0.42 [0.29; 0.56]	0.88 [0.74; 1.02]	t = −6.48,
	DH group, n = 34	0.48 [0.34; 0.63]	0.76 [0.66; 0.85]	t = −3.29,

EO (abs, 10⁹/l)	n = 65	0.044 [0.013; 0.075]	0.270 [0.209; 0.331]	t = −6.65,
	FH group, n = 31	0.023 [0.007; 0.038]	0.298 [0.207; 0.389]	t = −5.43,
	DH group, n = 34	0.061 [0.005; 0.117]	0.247 [0.159; 0.334]	t = −4.15,

WBC: white blood cell count; RBC–red blood cell count; HGB: level of hemoglobin molecules; HCT: hematocrit; MCV: mean corpuscular volume of red blood cells; MCH: mean corpuscular hemoglobin; PLT: platelet levels in the blood; NEUT: neutrophil granulocyte; MONO: monocyte; LYM: lymphocyte; EO: eosinophil granulocyte; MPV: mean platelet volume; P-LCR: platelet large cell ratio; abs.: absolute cells count.