Association between Circulating Growth Differentiation Factor 15 and Cirrhotic Primary Biliary Cholangitis

Table 4

Clinical and laboratory parameters of biochemical responders and non-responders in cirrhotic PBC patients.

Feature	Biochemical responders ()	Biochemical non-responder ()	value
Age (years)			0.859
Gender (male)	3	4	0.651
GDF15 (pg/mL)			0.014
Weight changes (kg)			0.209
ALT (U/L)			0.877
AST (U/L)			0.211
TBIL (μmol/L)			0.003
DBIL (μmol/L)			0.008
GGT (U/L)			0.536
ALP (U/L)			0.249
TBA (μmol/L)			0.097
ALB (g/L)			0.059
GLB (g/L)			0.819
INR			0.040
CRP (mg/L)			0.038
MELD score			0.135
Mayo risk score			0.002

PBC: primary biliary cholangitis; GDF15: growth differentiation factor 15; AST: aspartate aminotransferase; ALT: alanine aminotransferase; TBIL: total bilirubin; DBIL: direct bilirubin; GGT: gamma-glutamyl transpeptidase; ALP: alkaline phosphatase; TBA: total bile acids; ALB: albumin; GLB: globulin; INR: international normalized ratio; CRP: C-reactive protein; MELD score: Model for End-stage Liver Disease score.