Clinical Study

A Novel Diagnostic Nomogram for Noninvasive Evaluating Liver Fibrosis in Patients with Chronic Hepatitis B Virus Infection

Table 1

Comparing patients’ baseline demographic characteristics and clinical and pathological data between training dataset and validation dataset.

CharacteristicsTraining datasetValidation dataset
(%) (%)

Gender
 Male237 (66.76)97 (63.40)0.464
 Female118 (33.24)56 (36.60)
Age (yrs)0.828
Significant fibrosis
 No209 (58.87)92 (60.13)0.791
 Yes146 (41.13)61 (39.87)
LSM (kPa)0.293
Laboratory data
 ALT (IU/L)0.730
 AST (IU/L)0.549
 TBIL (μmol/L)0.541
 DBIL (μmol/L)0.520
 ALP (IU/L)0.773
 GGT (IU/L)0.793
 CHE (IU/L)0.540
 TP (g/L)0.951
 ALB (g/L)0.277
 GLO (g/L)0.721
 WBC (×109/L)0.541
 RBC (×1012/L)0.067
 HGB (g/L)0.224
 PLT (×109/L)0.055
 PT (S)0.892

Data were presented as (%), , or median (interquartile range). LSM: liver stiffness measurement; ALT: alanine aminotransferase; AST: aspartate aminotransferase; TBIL: total bilirubin; DBIL: directed bilirubin; ALP: alkaline phosphatase; GGT: γ-glutamyl transferase; CHE: cholinesterase; TP: total protein; ALB: albumin; GLO: globulin; WBC: white blood cell; RBC: red blood cell; HGB: hemoglobin; PLT: platelet count; PT: prothrombin time.