Both Gut Microbiota and Differentially Expressed Proteins Are Relevant to the Development of Obesity

Figure 3

Gut microbial changes at four different time points. (a) Histograms of α-diversity (as assessed by the Shannon index) based on OTUs in HFD and SD mice. (b) Beta diversity was assessed by PCoA based on the OTUs of separate groups. (c) Relative abundance levels of the top 10 phyla between the two groups. (d) LEfSe analysis illustrated significant differences in the gut microbiota. The cladogram represents the taxonomic level of the phylum to the genus from inside to outside. The diameter of the circle is proportionated to each taxon’s mean relative abundance. (e, f) Cladograms corresponding to the SD and HFD groups, respectively.

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