The Correlation between PSCA Expression and Neuroendocrine Differentiation in Prostate Cancer

Table 4

Correlation among immunohistochemical markers in clinicopathological factors.

Marker expression	PSA	PSCA	NSE
General preoperative PSA level
PSA
	NA	0.087	0.055
value	NA	0.348	0.552
PSCA
	0.087	NA	0.641^a
value	0.348	NA	<0.001
NSE
	0.055	0.64^a	NA
value	0.552	<0.001	NA
Preoperative
PSA
	NA	-0.361^a	-0.372^a
value	NA	0.036	0.030
PSCA
	-0.361^a	NA	0.685^a
value	0.036	NA	<0.001
NSE
	-0.372^a	0.685^a	NA
value	0.030	<0.001	NA
Patients with hormone therapy
PSA
	NA	0.180	0.201
value	NA	0.333	0.279
PSCA
	0.180	NA	0.587^a
value	0.333	NA	0.001
NSE
	0.201	0.587^a	NA
value	0.279	0.001	NA

Abbreviations: PSA: prostate-specific antigen; PSCA: prostate stem cell antigen; NSE: enolase 2. ^aCorrelation is significant at the level (test of significance, Spearman correlation).