The Correlation between PSCA Expression and Neuroendocrine Differentiation in Prostate Cancer

Table 5

Univariate and multivariate Cox logistic regression analysis of overall survival in patients with prostate cancer.

Clinicopathological features	Univariate			Multivariate
	HR	95% CI	value	HR	95% CI	value
Age	1.308	0.563-3.039	0.533
Preoperative PSA level	1.328	0.783-2.253	0.293
Gleason score	2.313	1.299-4.118	0.004	1.347	0.630-2.878	0.442
pT stage	1.538	0.672-3.520	0.308
Metastasis status	3.363	1.390-8.134	0.007	1.572	0.564-4.387	0.387
Hormone therapy	0.306	0.072-1.308	0.110
PSCA expression level	10.068	1.355-74.805	0.024	4.250	0.466-38.734	0.199
NSE expression level	3.841	1.647-8.957	0.002	1.711	0.638-4.584	0.286
Surgical intervention	2.346	1.014-5.428	0.046	1.750	0.730-4.192	0.210

Abbreviations: HR: hazard ratio; CI: confidence interval; pT stage: pathologic tumor stage; PSCA: prostate stem cell antigen; NSE: enolase 2.