Research Article
Chromodomain Helicase DNA-Binding Protein 5 Inhibits Renal Cell Carcinoma Tumorigenesis by Activation of the p53 and RB Pathways
Table 1
Correlation between CHD5 expression levels and clinicopathological features in RCC patients.
| Variables | Number (%) | mRNAa () | value | Proteinb () | value |
| Gender | | | | | | Male | 17 (70.8) | | 0.573 | | 0.508 | Female | 7 (29.2) | | | Age | | | | | | <60 | 14 (58.3) | | 0.071 | | 0.101 | ≥60 | 10 (41.7) | | | Tumor size | | | | | | <7 | 14 (58.3) | | 0.069 | | 0.061 | ≥7 | 10 (41.7) | | | TNM stage | | | | | | I-II | 13 (54.2) | | <0.001 | | 0.008 | III-IV | 11 (45.8) | | | Fuhrman grade | | | | | | I-II | 12 (50.0) | | 0.004 | | 0.057 | III-IV | 12 (50.0) | | | Lymph node metastasis | | | | | | Yes | 6 (25.0) | | 0.002 | | 0.028 | No | 18 (75.0) | | |
|
|
aRelative expression of CHD5 ratio by RT-qPCR. bGrayscale ratio by western blot.
|