Research Article

Chromodomain Helicase DNA-Binding Protein 5 Inhibits Renal Cell Carcinoma Tumorigenesis by Activation of the p53 and RB Pathways

Table 1

Correlation between CHD5 expression levels and clinicopathological features in RCC patients.

VariablesNumber (%)mRNAa () valueProteinb () value

Gender
 Male17 (70.8)0.5730.508
 Female7 (29.2)
Age
 <6014 (58.3)0.0710.101
 ≥6010 (41.7)
Tumor size
 <714 (58.3)0.0690.061
 ≥710 (41.7)
TNM stage
 I-II13 (54.2)<0.0010.008
 III-IV11 (45.8)
Fuhrman grade
 I-II12 (50.0)0.0040.057
 III-IV12 (50.0)
Lymph node metastasis
 Yes6 (25.0)0.0020.028
 No18 (75.0)

aRelative expression of CHD5 ratio by RT-qPCR. bGrayscale ratio by western blot.