Validation of the Combined Model Based on Platelet Count and Albumin to Rule out High-Risk Varices in Liver Cirrhosis

Table 3

Need for EGD based on noninvasive criteria for ruling out high-risk varices.

	Pooled cohort (292patients)
Characteristics	B6C ()	EB6C ()	RESIST-HCV ()
AUROC	0.599	0.615	0.710
^aSpared EGD, (%)	14 (15.6)	21 (23.3)	109 (37.3)
^bMissed HRV, (%)	0 (0)	1 (4.8)	1 (0.9)
NPV (%)	100	95.2	99.1
Sen (%)	100	94.7	97.9
Spe (%)	19.7	28.2	44.1
PPV (%)	25	26.1	25.1

Abbreviations: AUROC: area under receiving operator characteristics curve; B6C: Baveno VI criteria; EB6C: expanded Baveno VI criteria; EGD: esophagogastroduodenoscopy; HRV: high-risk varices; NPV: negative predictive value; PPV: positive predictive value; Sen: sensitivity; Spe: specificity. ^aThe spared EGD rate was calculated as the ratio between the number of patients with EGD that could be spared and the total number of patients. ^bThe missed HRV rate was defined as the rate of patients with missed HRV among the patients with spared EGD.