Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells

<div>LCA attenuated the viability and promoted apoptosis of HCT-116 cells in a dose-dependent manner. (a) The chemical structure of LCA. (b) Cell viability was measured using MTT assay. (c) Cell cycle was detected by flow cytometry. (d) Apoptosis was evaluated using flow cytometry. (e) Apoptosis- and cell cycle-related proteins were detected by western blot. 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BioMed Research International

fig1

Figure 1

Figure 1: Licochalcone a Induces ROS-Mediated Apoptosis through TrxR1 Inactivation in Colorectal Cancer Cells 