Inhibition of Macrophage Migration Inhibitory Factor Protects against Inflammation through a Toll-like Receptor-Related Pathway after Diffuse Axonal Injury in Rats

Figure 5

MIF inhibition attenuates glial responses and protects against ultrastructural alterations of axons. (a) Ultrastructural alterations of the longitudinal sections of axons after DAI were observed by TEM (, ). (b) GFAP and Iba-1 were assessed via immunohistochemistry in rat cortices. . Data are presented as (; compared with the control group; ^# compared with the DAI 1 d + ISO-1 group).

(a)

(b)