BioMed Research International / 2020 / Article / Fig 3

Research Article

Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response

Figure 3

Establishment of LPS-stimulated THP-1 sepsis model. (a, b) Immunoblots showing caspase-1 and GSDMD levels in the THP-1 treated with LPS for 0, 4, 8, 12, and 24 h. (c). LDH content in the supernatant at the different time points. (d, e) IL-1β and IL-18 secretion in the supernatant following LPS stimulation. , , , and .

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