Rapamycin Inhibited Pyroptosis and Reduced the Release of IL-1β and IL-18 in the Septic Response
RAPA abrogates the effect of 4 h LPS stimulation in THP-1. (a, b) Immunoblot showing the levels of caspase-1, GSDMD, LC3II, and LC3I. (c) Relative concentration of LDH in the supernatant. (d) IL-1β and (e) IL-18 content released into the supernatant. and .
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