Photodynamic Therapy Using HMME for Port-Wine Stains: Clinical Effectiveness and Sonographic Appearance

Table 2

Observation on the efficacy of HMME-PDT in the treatment of PWS.

	Number of cases	Efficacy assessment				Statistics
		Cured	Marked effective	Effective	Ineffective
Gender
Male	9	1 (11.11)	4 (44.44)	3 (33.33)	1 (11.11)
Female	36	9 (25.00)	17 (47.22)	10 (27.78)	0 (0.00)
Age
<18	6	4 (66.67)	1 (16.67)	1 (16.67)	0 (0.00)
18 to 29	30	4 (13.33)	16 (53.33)	10 (33.33)	0 (0.00)
>29	9	2 (22.22)	4 (44.44)	2 (22.22)	1 (11.11)
Lesion distribution
Cheek	24	5 (20.83)	14 (58.33)	5 (20.83)	0 (0.00)
Frontal	8	2 (25.00)	3 (37.50)	3 (37.50)	0 (0.00)
Mandibular and Ankle	8	3 (37.50)	2 (25.00)	3 (37.50)	0 (0.00)
Middle	2	0 (0.00)	0 (0.00)	2 (100.00)	0 (0.00)
Other parts	3	0 (0.00)	2 (66.67)	0 (0.00)	1 (33.33)
Degree of lesion
Pink type	5	5 (100.00)	0 (0.00)	0 (0.00)	0 (0.00)
Purple red	39	5 (12.82)	21 (53.85)	13 (33.33)	0 (0.00)
Thickened	1	0 (0.00)	0 (0.00)	0 (0.00)	1 (100.00)

Notes: the efficacy of HMME-PDT in the treatment of PWS was observed by the Mann-Whitney test. There was no significant difference between the sexes (). The Kruskal-Wallis test showed that there were significant differences in the efficacy among different age groups (). The group under 18 years old had the best efficacy, and there was no significant difference in the efficacy between different lesion distribution (). Because there was only one case of the hypertrophic type, it was not involved in the statistical analysis. The Mann-Whitney test showed that there were significant differences in the curative effect among different degrees of lesion (). The pink type showed the best curative effect, followed by the purple-red type.