Research Article

Prognostic Value of Thyroid Hormone FT3 in General Patients Admitted to the Intensive Care Unit

Table 1

Baseline of characteristics of the study subjects.

VariableTotal ()NTIS ()Non-NTIS ()

Males (%)31.530.532.10.96
Age (years)0.06
Principal diagnosis leading to ICU admission (%)<0.001
 Sepsis or sepsis shock31256
 Bodily injury1374499
 Brain injury711853
 Severe disease of medicine23914
 After operation321814
 Tumor972
 Pulmonary embolism211
APACHE II score<0.001
GCS score0.97
SOFA score<0.001
FT3 (pmol/L)<0.001
FT4 (pmol/L)0.001
TSH (mIU/L)0.148
Vital signs when enrolled
(°C)0.387
 HR0.172
 SBP (mmHg)0.149
 DBP (mmHg)0.134
 RR0.448
ALB (g/L)0.001
PCT (μg/L)0.02
BNP (pg/mL)0.003
WBC (×109/L)0.222
HGB (g/L)
 PLT (×109/L)0.016
 PT (s)0.101
 APTT (s)0.032
 FIB (g/L)0.848
 Lactic acid (mmol/L)0.113
 PCO2 (mmHg)0.379
Oxygenation index (PaO2/FIO2)0.535
CREA (μmol/L)0.006
TBil (mmol/L)0.084
Na (mmol/L)0.744
K (mmol/L)0.664

NTIS: nonthyroidal illness syndrome; APACHE II score, acute physiology and chronic health evaluation II score; GCS: Glasgow coma scale; SOFA: sequential organ failure score; FT3: free triiodothyronine; FT4; free thyroxine; TSH: thyroid-stimulating hormone; : temperature; HR: heart rate; SBP: systolic blood pressure; DBP: diastolic blood pressure; RR: respiratory rate; ALB: albumin; PCT: procalcitonin; BNP; brain natriuretic peptide; WBC: white blood cell; HGB: hemoglobin; PLT: blood platelet; PT: prothrombin time; APTT: activated partial thromboplastin time; FIB: fibrinogen; PCO2: pressure of carbon dioxide; PaO2: pressure of oxygen; FIO2: fraction of inspired oxygen; CREA: creatinine; TBil: total bilirubin.