Research Article
Fractionated Stereotactic Radiation Therapy Using Volumetric Modulated Arc Therapy in Patients with Solitary Brain Metastases
Table 2
Univariate and multivariate Cox analysis of covariates related to local failure.
| Variables | Univariate | value | Multivariate | value | Hazard ratio (95% CI) | Hazard ratio (95% CI) |
| Gender (male vs. female) | 0.31 (0.034-2.75) | 0.291 | — | — | Age (18-59 years vs. ≥60 years) | 0.76 (0.13-4.55) | 0.762 | — | — | Histology (NSCLC vs. breast) | 0.39 (0.07-2.33) | 0.301 | — | — | Histology (NSCLC vs. others) | 0.00 (0.00-+inf) | 0.998 | — | — | Tumor diameter (cm) | 3.97 (1.38-11.43) | 0.011 | — | — | Fraction dose (Gy) | 0.16 (0.047-0.54) | 0.003 | 0.14 (0.019-0.95) | 0.046 | PTV margin (0 vs. 1 mm) | 7.09 (0.78-64.53) | 0.082 | — | — |
|
|
NSCLC: non-small-cell lung cancer; CI: confidence interval; PTV: planning target volume.
|