Alternative Polyadenylation Modification Patterns Reveal Essential Posttranscription Regulatory Mechanisms of Tumorigenesis in Multiple Tumor Types

Figure 1

Entire procedures for the analysis of TCGA-APA data in different cancer types. The data is first analysed by the minimum redundancy maximum relevancy (mRMR) method, yielding a feature list. Then, incremental feature selection (IFS), incorporating a support vector machine, is applied on the list to extract important APA-associated genes and build an efficient classifier.