Intermittent Hypoxic Exposure Reduces Endothelial Dysfunction

Table 2

Pro- and anti-inflammatory markers of atherosclerosis before and after 6-day intermittent hypoxic exposure (, Me).

	Control				1^st day vs. 6^th day	IHE				1^st day vs. 6^th day	Control vs. IHE 6^th day, value
	1^st day,		6^th day,			1^st day,		6^th day,
		Me		Me			Me		Me
TNFα (pg/mL)		3.82		3.71	>0.05		3.93		4.04	>0.05	>0.05
IL-1β (pg/mL)		2.05		2.44	>0.05		2.03		2.64	<0.05	>0.05
hsCRP (mg/L)		1.28		1.82	>0.05		1.45		2.61	<0.05	<0.05
H2O2 (μmol/L)		12.25		11.07	>0.05		11.91		16.40	< 0.05	<0.05
NO (μmol/L)		13.55		13.45	>0.05		13.09		24.35	<0.05	<0.05
3NT (nmol/L)		41.53		51.19	< 0.05		42.64		34.47	<0.05	<0.05
HSP27 (pg/mL)		734		696	>0.05		747		814	<0.05	<0.05

Abbreviations: TNFα: tumour necrosis factor α; IL-1β: interleukin 1β; hsCRP: high sensitivity C-reactive protein; H₂O₂: hydrogen peroxide; NO: nitric oxide; 3NT: 3-nitrotyrosine; HSP27: heat stress protein 27; SEM: standard error of the mean; Me: median.