Research Article
Intermittent Hypoxic Exposure Reduces Endothelial Dysfunction
Table 2
Pro- and anti-inflammatory markers of atherosclerosis before and after 6-day intermittent hypoxic exposure (
, Me).
| | Control | 1st day vs. 6th day | IHE | 1st day vs. 6th day | Control vs. IHE 6th day, value | 1st day, | | 6th day, | 1st day, | 6th day, | | Me | | Me | | | Me | | Me |
| TNFα (pg/mL) | | 3.82 | | 3.71 | >0.05 | | 3.93 | | 4.04 | >0.05 | >0.05 | IL-1β (pg/mL) | | 2.05 | | 2.44 | >0.05 | | 2.03 | | 2.64 | <0.05 | >0.05 | hsCRP (mg/L) | | 1.28 | | 1.82 | >0.05 | | 1.45 | | 2.61 | <0.05 | <0.05 | H2O2 (μmol/L) | | 12.25 | | 11.07 | >0.05 | | 11.91 | | 16.40 | < 0.05 | <0.05 | NO (μmol/L) | | 13.55 | | 13.45 | >0.05 | | 13.09 | | 24.35 | <0.05 | <0.05 | 3NT (nmol/L) | | 41.53 | | 51.19 | < 0.05 | | 42.64 | | 34.47 | <0.05 | <0.05 | HSP27 (pg/mL) | | 734 | | 696 | >0.05 | | 747 | | 814 | <0.05 | <0.05 |
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Abbreviations: TNFα: tumour necrosis factor α; IL-1β: interleukin 1β; hsCRP: high sensitivity C-reactive protein; H2O2: hydrogen peroxide; NO: nitric oxide; 3NT: 3-nitrotyrosine; HSP27: heat stress protein 27; SEM: standard error of the mean; Me: median.
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