Research Article
Irisin Pretreatment Protects Kidneys against Acute Kidney Injury Induced by Ischemia/Reperfusion via Upregulating the Expression of Uncoupling Protein 2
Figure 2
Irisin suppresses the cellular inflammatory response and facilitates oxidative stress in mice after I/R injury. Representative photographs from (a) immunohistochemical and (b) semiquantitative analyses of ICAM-1 and P-selectin. Magnification, 400x. . (c) The level of TNF-α measured by ELISA. (d) Representative images of Western blotting of IL-1β and IL-6. (e) MPO and (f) SOD and MDA production in the kidney ( experiments). Data are presented as . ; ; . Abbreviations: NS: no significant difference.
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