Integrated Analysis of a Gene Correlation Network Identifies Critical Regulation of Fibrosis by lncRNAs and TFs in Idiopathic Pulmonary Fibrosis

Figure 1

Identification of DEGs from three GEO datasets (GSE2052, GSE44723, and GSE24206). (a–c) Volcano plot of the distributions of DEGs from the three datasets, mapping upregulated genes (red dots) and downregulated genes (blue dots). No significantly changed genes are marked as gray dots. (d) Identification of 29 commonly changed DEGs using Venn diagram from these three datasets (http://www.ehbio.com/ImageGP/index.php/Home/). Differently colored areas represented different datasets. The overlap areas meant the commonly changed DEGs. DEGs were identified with a paired -test. The value of less than 0.05 and [logFC] value of more than 1 were considered statistically significant.

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