Research Article
Integrated Analysis of a Gene Correlation Network Identifies Critical Regulation of Fibrosis by lncRNAs and TFs in Idiopathic Pulmonary Fibrosis
Table 2
The significantly enriched analysis of differentially expressed genes in idiopathic pulmonary fibrosis.
| Category | Pathway ID | Description | Count | value |
| GOTERM_BP | GO:0007155 | Cell adhesion | 45 | | GOTERM_BP | GO:0022610 | Biological adhesion | 45 | | GOTERM_BP | GO:0042127 | Regulation of cell proliferation | 42 | | GOTERM_BP | GO:0035295 | Tube development | 18 | | GOTERM_BP | GO:0032103 | Positive regulation of response to external stimulus | 10 | | GOTERM_BP | GO:0001501 | Skeletal system development | 22 | | GOTERM_MF | GO:0005509 | Calcium ion binding | 38 | 0.000949643 | GOTERM_MF | GO:0019955 | Cytokine binding | 10 | 0.001081524 | GOTERM_MF | GO:0008009 | Chemokine activity | 6 | 0.004374834 | GOTERM_MF | GO:0042802 | Identical protein binding | 27 | 0.00485805 | GOTERM_MF | GO:0042379 | Chemokine receptor binding | 6 | 0.005747644 | GOTERM_MF | GO:0008017 | Microtubule binding | 7 | 0.00692901 | GOTERM_CC | GO:0044421 | Extracellular region part | 54 | | GOTERM_CC | GO:0005615 | Extracellular space | 38 | | GOTERM_CC | GO:0031012 | Extracellular matrix | 24 | | GOTERM_CC | GO:0005578 | Proteinaceous extracellular matrix | 22 | | GOTERM_CC | GO:0044459 | Plasma membrane part | 76 | | GOTERM_CC | GO:0031226 | Intrinsic to plasma membrane | 48 | 0.000103242 | KEGG_PATHWAY | hsa04512 | ECM-receptor interaction | 9 | 0.00286045 | KEGG_PATHWAY | hsa04060 | Cytokine-cytokine receptor interaction | 17 | 0.003658523 | KEGG_PATHWAY | hsa04510 | Focal adhesion | 13 | 0.01357663 | KEGG_PATHWAY | hsa04610 | Complement and coagulation cascades | 7 | 0.014586106 | KEGG_PATHWAY | hsa05414 | Dilated cardiomyopathy | 8 | 0.017081193 | KEGG_PATHWAY | hsa00360 | Phenylalanine metabolism | 4 | 0.024804532 |
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