Research Article

Integrated Analysis of a Gene Correlation Network Identifies Critical Regulation of Fibrosis by lncRNAs and TFs in Idiopathic Pulmonary Fibrosis

Table 2

The significantly enriched analysis of differentially expressed genes in idiopathic pulmonary fibrosis.

CategoryPathway IDDescriptionCount value

GOTERM_BPGO:0007155Cell adhesion45
GOTERM_BPGO:0022610Biological adhesion45
GOTERM_BPGO:0042127Regulation of cell proliferation42
GOTERM_BPGO:0035295Tube development18
GOTERM_BPGO:0032103Positive regulation of response to external stimulus10
GOTERM_BPGO:0001501Skeletal system development22
GOTERM_MFGO:0005509Calcium ion binding380.000949643
GOTERM_MFGO:0019955Cytokine binding100.001081524
GOTERM_MFGO:0008009Chemokine activity60.004374834
GOTERM_MFGO:0042802Identical protein binding270.00485805
GOTERM_MFGO:0042379Chemokine receptor binding60.005747644
GOTERM_MFGO:0008017Microtubule binding70.00692901
GOTERM_CCGO:0044421Extracellular region part54
GOTERM_CCGO:0005615Extracellular space38
GOTERM_CCGO:0031012Extracellular matrix24
GOTERM_CCGO:0005578Proteinaceous extracellular matrix22
GOTERM_CCGO:0044459Plasma membrane part76
GOTERM_CCGO:0031226Intrinsic to plasma membrane480.000103242
KEGG_PATHWAYhsa04512ECM-receptor interaction90.00286045
KEGG_PATHWAYhsa04060Cytokine-cytokine receptor interaction170.003658523
KEGG_PATHWAYhsa04510Focal adhesion130.01357663
KEGG_PATHWAYhsa04610Complement and coagulation cascades70.014586106
KEGG_PATHWAYhsa05414Dilated cardiomyopathy80.017081193
KEGG_PATHWAYhsa00360Phenylalanine metabolism40.024804532