Uridine Metabolism and Its Role in Glucose, Lipid, and Amino Acid Homeostasis

Figure 1

De novo synthesis of uridine: ① carbamoyl phosphate synthetase (CPS II); ② aspartate transcarbamoylase (ATCase); ③ dihydroorotase (DHO); ④ dihydroorotate dehydrogenase (DHODH); ⑤ orotate phosphoribosyltransferase; ⑥ orotidine 5-phosphate decarboxylase; ⑦ nucleotidase; ⑧ uridine phosphorylase.