Review Article

Associated Targets of the Antioxidant Cardioprotection of Ganoderma lucidum in Diabetic Cardiomyopathy by Using Open Targets Platform: A Systematic Review

Table 2

Nineteen pathway types involved in the heart tissues of 155 targets expressed.

No.Pathway (No. of targets)

1.Signal transduction (63)
2.Immune system (47)
3.Metabolism of proteins (39)
4.Metabolism (31)
5.Gene expression (transcription) (25)
6.Hemostasis (23)
7.Disease (22)
8.Developmental biology (20)
9.Extracellular matrix organization (18)
10.Cellular responses to external stimuli (14)
11.Transport of small molecules (11)
12.Muscle contraction (11)
13.Vesicle-mediated transport (10)
14.Organelle biogenesis and maintenance (4)
15.Programmed cell death (4)
16.Autophagy (4)
17.Neuronal system (3)
18.Cell cycle (3)
19.Circadian clock (3)