miR-30e-3p Promotes Cardiomyocyte Autophagy and Inhibits Apoptosis via Regulating Egr-1 during Ischemia/Hypoxia
miR-30e-3p overexpression attenuates apoptosis in IH-exposed cardiomyocytes. (a) Apoptosis measured using flow cytometry. (b) Summarized apoptosis indexes. (c) Quantification of cleaved caspase 3 protein levels. (d) Cleaved caspase 3 protein expression levels determined by western blot (; and , compared to the control group; △ and △△, compared to the IH group; ▽ and ▽▽, compared to the IH+MIR group). Con: control; NC: negative control; IH: ischemia/hypoxia; MIR: miR-30e-3p; 3-MA: 3-methyladenine; LDH: lactate dehydrogenase; C-caspase 3: cleaved caspase 3.
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