The Efficacy of Traditional Chinese Medicine Shoutai Pill Combined with Western Medicine in the First Trimester of Pregnancy in Women with Unexplained Recurrent Spontaneous Abortion: A Systematic Review and Meta-Analysis

Table 3

The summary of GRADE evaluation.

Outcomes	Participants (studies)	RR/SMD (95% CI)	GRADE	Comments
The incidence of early pregnancy loss	876 (11 RCTs)	0.42 (0.34,0.52)	⨁⨁⨁◯ Moderate	“Risk of bias” was downgraded to “serious”
TCM syndromes and symptoms	549 (8 RCTs)	-2.39 (-2.86, -10.93)	⨁⨁◯◯ Low	“Risk of bias” was downgraded to “serious”; “Inconsistency” was downgraded to “serious”
Serum D-dimer level	256 (4 RCTs)	-0.25 (-0.30, -0.20)	⨁⨁⨁◯ Moderate	“Risk of bias” was downgraded to “serious”
Live birth rate	313 (5 RCTs)	1.81 (1.46, 2.25)	⨁⨁⨁◯ Moderate	“Risk of bias” was downgraded to “serious”

RR: Risk Ratio; SMD: Standard Mean Difference; RCT: Random controlled trial.