Research Article
tRNA-Derived Fragments in Podocytes with Adriamycin-Induced Injury Reveal the Potential Mechanism of Idiopathic Nephrotic Syndrome
Table 2
Target genes of differently expressed tRFs.
| | tRF ID | Type | Putative targets (target score ≥90) | Log2FC | value |
| | AS-tDR-011816 | tRF-3 | Afap1l2 | 8.42 | <0.001 | | AS-tDR-016239 | i-tRF | Cntd1; Ptpn20; Tead1; Dennd1b; Bach2; Tmbim6; Lgr4; 1700057G04Rik; Arhgap23; Mycn; Grip1 | 8.38 | <0.001 | | AS-tDR-016240 | i-tRF | Plpp3; Spred1; Fyn; Rnf139; Rbm24; Kcnq5; Lrp1; Tex21; Slc38a2; Lrrc19; Tmem165; Arpp19; Gfap; B3galt2; Lrif1; Rbms1; Asf1a; Ubl3; Zhx3; Sema6d; Kcnb2; Nkrf; Aebp2 | 8.38 | <0.001 | | AS-tDR-008924 | tRF-1 | Cd300lb; Phip; Slc6a8; Clec16a; Cd84; Tspear; Cacna2d2; Cx3cl1; Jpt1; 2900026A02Rik; Ywhah; Bloc1s6; Gpr158; Pax8 | 8.35 | <0.001 | | AS-tDR-011827 | tRF-1 | Limk1; Ngef | 7.88 | <0.001 | | AS-tDR-011031 | tRF-5 | Egfl6; Ash1l; Rab2a; Gna11; Rictor; Il6st; 4930402H24Rik; Rab23; Gorab; Rab12; Kif5b; Wasl; Fmnl2; Gpatch11; Zeb2; Fmn1; Utrn; Fam208b; Itgav; Ptpn23; Osbp; Akt1s1; Taok1; Kdelr2; Kat2b; Hectd1; Rac1; Acbd5; Bod1; Strn3; Cfl2; Tgfbr1; Mark3; Fyco1; Slc37a3; Tardbp; Fkbp1a; Atf7ip; Inpp5a; Twf1; Smug1; Dirc2; Stam; Tnrc18; Tnks; Fabp4; Suco; Morf4l2; Hgs; Atp2a2; Pawr; Rock2; Tab2; Arntl; Rheb; Tor1aip2 | 7.67 | <0.001 | | AS-tDR-016258 | i-tRF | Plpp3; Spred1; Fyn; Rnf139; Rbm24; Kcnq5; Lrp1; Tex21; Slc38a2; Lrrc19; Tmem165; Arpp19; Gfap; B3galt2; Lrif1; Rbms1; Asf1a; Ubl3; Zhx3; Sema6d; Kcnb2; Nkrf; Aebp2 | 7.67 | <0.001 | | AS-tDR-006555 | tRF-3 | Mdga2; Slc2a9; Clec10a; Foxj1; Elavl3; Gstt1; Slc8a1; Neurl1a; Sash3; Ppp3r1; Ptov1; Ubp1; Sirt1; 6720489N17Rik; Nufip2; Ranbp9 | 7.61 | <0.001 | | AS-tDR-001008 | tRF-5 | Slain1; Rac1 | 7.49 | <0.001 | | AS-tDR-007319 | tRF-5 | Slain1; Rac1 | 7.49 | <0.001 | | AS-tDR-007229 | i-tRF | Aak1; Pgm3; Zfp935; Pcmtd2; Pgf; Krt5; Boc; 6720489N17Rik; Gcnt2; Zfp930; AW209491; Mynn; En1; Fam168a; Tbx4; Zfp960; Zfp97; Slc9c1; Satb1; Fryl; Ntm; Ikbip; Eml6; Zfp951; Ptprb; Psme3; Elmod1; Acvr2b; Map4k2; Fshr; Egln1; Ubn1; Hs3st1; Trmt2b; Phka1 | -8.03 | <0.001 | | AS-tDR-004492 | i-tRF | Cbx3; Trpv5; Mgea5; Lhx9; Mmp12; Dlgap4; Amfr; Slc18a2 | -8.07 | <0.001 | | AS-tDR-008570 | i-tRF | Wif1 | -8.27 | <0.001 | | AS-tDR-008594 | i-tRF | Usp21; Unc79; Tmem56; Btbd1; Mmd; Phip; Prtg; Trim33; Cep44; Plxna2; Pappa; Runx1; Sema3e; Dpp10; Kdm6b; Gmfb; Ptchd3; Mtdh; Ube2e1; Npas3; Ocln; Adcyap1; Rab27b; Stk39; Arl8b; Kdm7a; Hcn1; Fut10; Htra4; Rap2c; Fos; Arl5a; Inpp5a; Steap2; Pcmtd1; Tm9sf1; Fadd; Dner; Bcl10; Cdyl2; Mtm1; Tfam; Cdc7; Lhcgr; Tfap4; Plekhm3; Ifih1; Pde1c; Lamp3; Synpr; Pclo; Rc3h1; Med13; Atxn3; Nefl; Map4k3; Eif4e; Naaladl2; Amd2; Fam126b; 4930430F08Rik; Itga4; Calm1; Mab21l2; Fshb; Usp47; Rgs8; Slc35a3; Tsc22d2; Lrrc36 | -8.27 | <0.001 | | AS-tDR-008586 | i-tRF | Usp21; Unc79; Tmem56; Btbd1; Mmd; Phip; Prtg; Trim33; Cep44; Plxna2; Pappa; Runx1; Sema3e; Dpp10; Kdm6b; Gmfb; Ptchd3; Mtdh; Ube2e1; Npas3; Ocln; Adcyap1; Rab27b; Stk39; Arl8b; Kdm7a; Hcn1; Fut10; Htra4; Rap2c; Fos; Arl5a; Inpp5a; Steap2; Pcmtd1; Tm9sf1; Fadd; Dner; Bcl10; Cdyl2; Mtm1; Tfam; Cdc7; Lhcgr; Tfap4; Plekhm3; Ifih1; Pde1c; Lamp3; Synpr; Pclo; Rc3h1; Med13; Atxn3; Nefl; Map4k3; Eif4e; Naaladl2; Amd2; Fam126b; 4930430F08Rik; Itga4; Calm1; Mab21l2; Fshb; Usp47; Rgs8; Slc35a3; Tsc22d2; Lrrc36 | -8.31 | <0.001 | | AS-tDR-003556 | i-tRF | Slc44a5; Nkx2-1 | -8.38 | <0.001 | | AS-tDR-013354 | i-tRF | Twistnb; Pcna; Ifi44; Tmem170b; Zfp37; Erich5; Rab21; Crot; Rfx3; Gnptg; Zfp616; Serpine2; Fgfr2; Msl3l2; Bicd1; Mtf2; Ank3; Fbxl5; Cdc40; Jarid2; Ppp1r36; Idh3a; Rfwd3; Cav2; Nufip2; Clns1a; Smim8; Tmem100; Sass6; Fmnl2; Akirin1 | -8.57 | <0.001 | | AS-tDR-003634 | i-tRF | Ifit2; Slc16a6; Rala; Epb41l2; Rnf19a; Fgf9; Bmp2; Pdgfra; Abhd5; Wnt9a; Dnm3; Klf9; Tgfbr1; Hdac7; Tssk2; Dpysl2; Bloc1s2; Ror1; Mpv17; Creb3l1; Katnbl1; Capn1; Mmd; Eif4g2; Zfp800; Ptgr2; Col4a3; Lrp4; Arhgef40; Heg1; Cps1; Kctd12b; Erc2; Car9; Cbll1; Med13; Ms4a10; Lhfpl2; Gm11487; Chac2; Entr1; Psma3; Rbbp4; Igfbp5; Wnt11; Vcpip1; Stradb; Nucks1; Coro2a; Naf1; Egr2; Tmem204; Galnt16; Vps18; Srcap; Hs2st1; Sept2; Strn3; Mlph; Vezf1; Rfx7; Dlgap1 | -8.74 | <0.001 | | AS-tDR-010713 | i-tRF | 1190002N15Rik | -8.82 | <0.001 | | AS-tDR-011690 | i-tRF | Adam7; Rlim; Simc1; Rwdd3; Slc35e2; Kat6b; Sptlc1; Irgm1; Brwd1; Gpr22 | -9.29 | <0.001 |
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Target score based on microRNA target prediction database. |
