Association between Insulin-Like Growth Factor-1 and Relative Skeletal Maturation: A Retrospective Cohort Study of Short Children and Adolescents
The association between the IGF-1 SDS and BA-CA before (a) () and after GH therapy (b) (). Adjustment variables: age, sex, BMI, pubertal stage, E2, T, LH, FSH. (b) Increased GH dose and GH treatment duration (). IGF-1 SDS: insulin-like growth factor-1 standard deviation score; BA-CA: bone age-chronological age; GH: growth hormone; BMI: body mass index.
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