Research Article

α-Glucosidase Inhibitor Can Effectively Inhibit the Risk of Tuberculosis in Patients with Diabetes: A Nested Case-Control Study

Table 2

Third quartile of the case and control group (from the index date to the endpoint).

ControlCase

Sulfonylureas
 Chlorpropamide, third
  None used (0 mg)6217 (99.89%)1554 (99.87%)
  Low concentration (≤third quartile)5 (0.08%)1 (0.06%)
  High concentration (>third quartile)2 (0.03%)1 (0.06%)
 Glibenclamide, third
  None used (0 mg)4251 (68.3%)988 (63.5%)
  Low concentration (≤third quartile)1387 (22.28%)422 (27.12%)
  High concentration (>third quartile)586 (9.42%)146 (9.38%)
 Glimepiride, third
  None used (0 mg)4033 (64.8%)986 (63.37%)
  Low concentration (≤third quartile)1476 (23.71%)393 (25.26%)
  High concentration (>third quartile)715 (11.49%)177 (11.38%)
 Gliclazide, third
  None used (0 mg)4039 (64.89%)961 (61.76%)
  Low concentration (≤third quartile)1530 (24.58%)436 (28.02%)
  High concentration (>third quartile)655 (10.52%)159 (10.22%)
 Tolbutamide, third
  None used (0 mg)6224 (100%)1556 (100%)
  Low concentration (≤third quartile)0 (0%)0 (0%)
  High concentration (>third quartile)0 (0%)0(0%)
 Tolazamide, third
  None used (0 mg)6180 (99.29%)1546 (99.36%)
  Low concentration (≤third quartile)30 (0.48%)8 (0.51%)
  High concentration (>third quartile)14 (0.22%)2 (0.13%)
Biguanides
 Metformin, third
  None used2414 (38.79%)541 (34.77%)
  Low concentration (≤third quartile)2717 (43.65%)757 (48.65%)
  High concentration (>third quartile)1093 (17.56%)258 (16.58%)
 Buformin, third
  None used6211 (99.79%)1550 (99.61%)
  Low concentration (≤third quartile)9 (0.14%)4 (0.26%)
  High concentration (>third quartile)4 (0.06%)2 (0.13%)
Meglitinides
 Repaglinide, third
  None used (0 mg)5434 (87.31%)1304 (83.8%)
  Low concentration (≤third quartile)484 (7.78%)169 (10.86%)
  High concentration (>third quartile)306 (4.92%)83 (5.33%)
 Nateglinide, third
  None used (0 mg)6062 (97.4%)1494 (96.02%)
  Low concentration (≤third quartile)105 (1.69%)35 (2.25%)
  High concentration (>third quartile)57 (0.92%)27 (1.74%)
α-Glucosidase inhibitor
 Acarbose, third
  None used (0 mg)4909 (78.87%)1233 (79.24%)
  Low concentration (≤third quartile)855 (13.74%)215 (13.82%)
  High concentration (>third quartile)460 (7.39%)108 (6.94%)
 Miglitol, third
  None used (0 mg)6181 (99.31%)1542 (99.1%)
  Low concentration (≤third quartile)18 (0.29%)9 (0.58%)
  High concentration (>third quartile)25 (0.4%)5 (0.32%)
Thiazolidinediones
 Rosiglitazone, third
  None used (0 mg)5355 (86.04%)1324 (85.09%)
  Low concentration (≤third quartile)599 (9.62%)175 (11.25%)
  High concentration (>third quartile)270 (4.34%)57 (3.66%)
 Pioglitazone, third
  None used (0 mg)5391 (86.62%)1348 (86.63%)
  Low concentration (≤third quartile)504 (8.1%)129 (8.29%)
  High concentration (>third quartile)329 (5.29%)79 (5.08%)

Population distribution of drug concentration.