Toxicokinetics of 11 Gelsemium Alkaloids in Rats by UPLC-MS/MS

Table 2

Regression equations and correlation coefficients for 11 Gelsemium alkaloids in rat plasma.

Compound	Linear range (ng/mL)	Regression equation	Correlation coefficient
Humantenirine	0.1-200		0.9962
Humantenine	0.1-200		0.9991
Akuammidine	0.1-200		0.9992
Gelsevirine	0.1-200		0.9995
Rankinidine	0.1-200		0.9987
n-Methoxyanhydrovobasinediol	0.1-200		0.9993
Gelsenicine	0.1-200		0.9985
Gelsemine	0.1-200		0.9967
Koumine	0.1-200		0.9980
Koumidine	0.1-200		0.9998
Sempervirine	0.1-200		0.9950

 = peak area ratio of Gelsemium alkaloids versus IS;  = concentration of Gelsemium alkaloids.