TRIM33 Overexpression Inhibits the Progression of Clear Cell Renal Cell Carcinoma In Vivo and In Vitro

Figure 5

TRIM33 overexpression can inhibit migration, invasion, and EMT in ccRCC; here, the potential molecular mechanisms are explored. (a and b) Wound healing assay. (c–e) Transwell assay, including migration and invasion experiments. (f–h) Western blot assay for TRIM33, E-cadherin, N-cadherin, vimentin, β-catenin, cyclin D1, c-myc, and β-actin. (i–k) Western blot assay after incubation with a Wnt signaling pathway agonist for β-catenin, cyclin D1, c-myc, and β-actin. ; ; ; ns represents no statistical significance.

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