MicroRNA-127 Inhibits the Progression of Melanoma by Downregulating Delta-Like Homologue 1

Figure 5

DLK1 was required for miR-127-mediated progression of melanoma. (a and b) Cell proliferation was measured in SK-MEL-2 and WM35 cells cotransfected with miR-127 + pcDNA or miR-127 + DLK1 by MTT assay. (c and d) Cell apoptosis was detected in SK-MEL-2 and WM35 cells cotransfected with miR-127 + pcDNA or miR-127 + DLK1 by flow cytometry. (e and f) The abundances of related proteins were examined in SK-MEL-2 and WM35 cells cotransfected with miR-127 + pcDNA or miR-127 + DLK1 by Western blot ().

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