Blood Monocyte Phenotype Fingerprint of Stable Coronary Artery Disease: A Cross-Sectional Substudy of SMARTool Clinical Trial

Table 2

Univariate and multivariate multinomial logistic regression analyses of blood monocyte subset frequency (%) and count (n° of cells/μl).

Subset frequency and count	Comparison between groups	Univariate regression coefficient	Unadjusted OR	95% CI	P	Adjusted OR^a	95% CI
Mon2 (%)	CAD1/CAD2; CAD1/CAD3	0.156; 0.193	1.169; 1.213	0.978-1.398; 1.017-1.447	Ns 0.0314	1.421; 1.550	1.043-1.936; 1.051-2.285	0.0260; 0.0269
Mon3 (%)	CAD1/CAD2; CAD1/CAD3	0.047; 0.125	1.048; 1.134	0.862-1.274; 0.936-1.372	Ns; Ns	1.351; 1.355	0.885-2.061; 0.865-2.125	Ns; Ns
Mon1 (/μl)	CAD1/CAD2; CAD1/CAD3	0.003; 0.001	1.003; 1.001	0.999-1.006; 0.996-1.005	Ns; Ns	0.999; 0.996	0.995-1.004; 0.988-1.003	Ns; Ns
Mon2 (/μl)	CAD1/CAD2; CAD1/CAD3	0.036; 0.039	1.036; 1.040	1.005-1.069; 1.008-1.073	0.0237; 0.0126	1.050; 1.059	0.998-1.105; 0.998-1.125	Ns; Ns
Mon3 (/μl)	CAD1/CAD2; CAD1/CAD3	0.025; 0.029	1.025; 1.029	0.993-1.058; 0.998-1.062	Ns; Ns	1.031; 1.014	0.974-1.091; 0.961-1.070	Ns; Ns

CAD: coronary artery disease; OR: odds ratio; CI: confidence interval; Ns: not significant. ^aAdjusted for Framingham Risk Score (FRS), metabolic syndrome, diabetes, Hs-CRP, IL-6, IFN-γ, TNF-α, IL-10, VCAM-1, ICAM-1, use and dosage of statin therapy (mg/die), and use of oral hypoglycemic drugs.