Research Article
Interactive Verification Analysis of Multiple Sequencing Data for Identifying Potential Biomarker of Lung Adenocarcinoma
Table 3
Top 40 DEGs, either up- or downregulated in LUAD, screened between normal lung tissues and LUAD tissues from 8 GEO series.
(a) |
| | Upregulated genes | | Gene | Log2FC | value |
| | SPINK1 | 4.41974 | 2.47-88 | | SPP1 | 3.73200 | 8.14-131 | | COL10A1 | 3.18065 | 7.47-118 | | EEF1A2 | 2.98860 | 3.87-59 | | CRABP2 | 2.97369 | 6.13-88 | | GCNT3 | 2.87337 | 5.06-68 | | MMP12 | 2.85476 | 6.44-69 | | MMP1 | 2.81899 | 2.73-55 | | MMP11 | 2.70584 | 1.42-66 | | TMPRSS4 | 2.65579 | 1.24-116 | | COL1A1 | 2.62413 | 1.70-88 | | TOP2A | 2.57396 | 3.07-94 | | CST1 | 2.57367 | 1.52-57 | | CEACAM5 | 2.55582 | 2.61-52 | | CDH3 | 2.55139 | 5.29-86 | | HMGB3 | 2.53340 | 7.97-110 | | S100P | 2.51783 | 6.32-34 | | PCP4 | 2.50192 | 5.64-54 | | COMP | 2.48062 | 1.14-56 | | ITPKA | 2.47468 | 1.30-53 | | CXCL13 | 2.44554 | 3.10-48 | | NMU | 2.43325 | 1.78-74 | | MMP9 | 2.42631 | 3.87-86 | | TK1 | 2.40426 | 7.22-81 | | UBE2C | 2.38795 | 1.61-102 | | LGSN | 2.34192 | 5.47-66 | | CDC20 | 2.32945 | 3.90-72 | | MELK | 2.27942 | 3.28-106 | | TPX2 | 2.24109 | 3.23-111 | | BIRC5 | 2.19958 | 9.24-79 | | CP | 2.16965 | 2.78-44 | | CXCL14 | 2.08959 | 9.80-42 | | HJURP | 2.08757 | 1.04-99 | | CRLF1 | 2.08375 | 3.08-35 | | PITX1 | 2.07558 | 2.05-38 | | SFN | 2.06306 | 1.89-53 | | CCNB1 | 2.06059 | 1.35-100 | | GREM1 | 2.05827 | 3.69-62 | | CENPF | 2.04220 | 9.45-110 | | PHLDA2 | 2.03621 | 6.31-63 |
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(b) |
| | Downregulated genes | | Gene | Log2FC | value |
| | CA4 | -4.46829 | 4.47-199 | | TMEM100 | -4.46722 | 1.04-163 | | FABP4 | -4.44449 | 1.28-204 | | AGER | -4.42758 | 1.32-187 | | FAM107A | -4.27770 | 1.13-199 | | FCN3 | -4.11945 | 5.98-158 | | HBA2 | -3.79644 | 2.07-159 | | SCGB1A1 | -3.77162 | 3.30-58 | | CLDN18 | -3.76781 | 5.36-131 | | SOSTDC1 | -3.71859 | 2.61-143 | | SLC6A4 | -3.71846 | 3.31-138 | | SFTPC | -3.67943 | 5.85-77 | | ADH1B | -3.64640 | 1.03-147 | | HBB | -3.64609 | 4.82-87 | | CYP4B1 | -3.61022 | 6.84-97 | | WIF1 | -3.60729 | 1.09-64 | | CAV1 | -3.58362 | 9.24-148 | | TCF21 | -3.51528 | 7.17-237 | | FHL1 | -3.38016 | 1.55-152 | | TNNC1 | -3.37549 | 4.89-157 | | PGC | -3.36845 | 1.21-60 | | LYVE1 | -3.31830 | 1.19-202 | | MFAP4 | -3.24097 | 1.82-125 | | FMO2 | -3.23925 | 5.63-181 | | CPB2 | -3.22462 | 1.35-89 | | SDPR | -3.17437 | 1.15-122 | | FOSB | -3.15933 | 1.39-65 | | MT1M | -3.05645 | 1.24-98 | | TGFBR3 | -3.03319 | 6.31-117 | | VIPR1 | -2.97732 | 8.36-112 | | PLA2G1B | -2.95468 | 2.22-97 | | HIGD1B | -2.93753 | 3.31-166 | | RAMP3 | -2.93655 | 4.44-131 | | CDH5 | -2.92926 | 6.30-146 | | TSPAN7 | -2.91740 | 4.02-107 | | GDF10 | -2.88654 | 2.28-148 | | CALCRL | -2.86974 | 1.15-145 | | BCHE | -2.80317 | 2.48-145 | | FOXF1 | -2.77773 | 1.35-136 | | RAMP2 | -2.77632 | 7.01-121 |
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