Bioinformatical Analysis of miRNA-mRNA Interaction Network Underlying Macrophage Aging and Cholesterol-Responsive Difference between Young and Aged Macrophages

Figure 2

miRNA-mRNA interactions underlying macrophage aging. miRNA-mRNA interaction analysis was conducted on the differentially expressed miRNAs and mRNAs in macrophage aging and 19 validated (a) and 544 predicted pairs (b) were identified. In addition, 83 highly predicted miRNA-mRNA pairs (c) were found which could be detected by four prediction databases.

(a)

(b)

(c)