Balloon-Occluded Trans-Arterial Chemo-Embolization Technique with Repeated Alternate Infusion of Cisplatin Solution and Sparse Gelatin Slurry (RAIB-TACE) for Large Hepatocellular Carcinoma Nodules More than 7 cm in Diameter

Table 1

Characteristics of patients and the large nodules.

Male : female	14 : 5
Age (years)	56–91 (mean: 75.6)
True rupture : impending one	2 : 4
Causes of hepatitis (B : C : alcohol : NASH : PBC : unknown)	0 : 10 : 2 : 5 : 1 : 1
Child-Pugh stage (A : B)	16 : 3
Elevation of AFP (>100)^1	8
Elevation of PIVKA-II (>100)^2	11
No. of nodules (solitary : 3 : >10)	7 : 4 : 8
BCLC stage (A : B : C : D)^3	6 : 11 : 0 : 2
Diameter of the large nodule (mm)	72–148 (mean: 99)
Dose of cisplatin (mg)	50–112 (mean: 79)

¹AFP: alpha-fetoprotein. ²PIVKA-II: protein induced by vitamin K absence or antagonists-II. ³The cause of stage D was performance status 4 due to Parkinson’s and Alzheimer’s diseases. The Child-Pugh stage of both cases was B. The mean diameter of the large nodules was 99 mm.