A Comparative Study of 2 Different Segmentation Methods of ADC Histogram for Differentiation Genetic Subtypes in Lower-Grade Diffuse Gliomas

Table 3

ADC histogram parameters for IDH^mut/1p19q⁺ tumors using different ROI methods.

Values (×10^-6 mm^2/s)	The tumor ROI	The tumor ROI excluding cystic or necrotic portions	Test values	values
ADCmean			0.713^a	0.481
ADCmin			-0.26^a	0.795
P5 ADC			0.147^a	0.884
P10 ADC			0.230^a	0.820
P25 ADC			0.287^a	0.776
P50 ADC			0.364^a	0.718
P75 ADC			0.959^a	0.344
P90 ADC			1.280^a	0.209
P95 ADC			1.609^a	0.117
ADCmax			2.145^a	0.044
ADCmode			-0.037^a	0.971
Kurtosis	-0.342 (-0.518, 1.988)	-0.354 (-0.482, 0.080)	-0.253^b	0.800
Skewness	-0.200 (-0.446, 0.912)	-0.227 (-0.526, 0.183)	-0.886^b	0.376
StDev	288.203 (215.733, 366.08)		-1.487^b	0.137
Inhomogenity	0.172 (0.155, 0.244)		-1.361^b	0.173
Range			2.007^a	0.057
Entropy			-0.944^a	0.352

^a, t value; ^b, Z value.