Serum miR-1228-3p and miR-181a-5p as Noninvasive Biomarkers for Non-Small Cell Lung Cancer Diagnosis and Prognosis

Table 5

ROC curve analysis of differential miRNAs.

miRNAs	AUC	P value	95% CI
			Lower	Upper
miR-1228-3p	0.685	0.006	0.563	0.806
miR-133a-3p	0.636	0.043	0.512	0.760
miR-545-3p	0.635	0.045	0.514	0.756
miR-181a-5p	0.647	0.049	0.506	0.758
miR-361-5p	0.635	0.045	0.508	0.761
miR-1228-3p + miR-133a-3p	0.615	0.087	0.490	0.739
miR-1228-3p + miR-545-3p	0.622	0.069	0.500	0.744
miR-1228-3p + miR-181a-5p	0.711	0.002	0.593	0.828
miR-1228-3p + miR-361-5p	0.651	0.025	0.520	0.781
miR-133a-3p + miR-545-3p	0.705	0.002	0.592	0.818
miR-133a-3p + miR-181a-5p	0.679	0.008	0.554	0.804
miR-133a-3p + miR-361-5p	0.637	0.041	0.510	0.764
miR-545-3p + miR-181a-5p	0.585	0.207	0.460	0.710
miR-545-3p + miR-361-5p	0.611	0.097	0.485	0.738
miR-181a-5p + miR-361-5p	0.646	0.030	0.520	0.772
miR-1228-3p + miR-133a-3p + miR-545-3p	0.698	0.003	0.585	0.811
miR-1228-3p + miR-133a-3p + miR-181a-5p	0.661	0.017	0.535	0.787
miR-1228-3p + miR-133a-3p + miR-361-5p	0.616	0.084	0.489	0.743
miR-1228-3p + miR-545-3p + miR-181a-5p	0.588	0.19	0.463	0.713
miR-1228-3p + miR-545-3p + miR-361-5p	0.609	0.105	0.483	0.735
miR-1228-3p + miR-181a-5p + miR-361-5p	0.647	0.029	0.517	0.776
miR-133a-3p + miR-545-3p + miR-181a-5p	0.609	0.103	0.486	0.733
miR-133a-3p + miR-545-3p + miR-361-5p	0.643	0.033	0.519	0.768
miR-133a-3p + miR-181a-5p + miR-361-5p	0.663	0.015	0.538	0.789
miR-545-3p + miR-181a-5p + miR-361-5p	0.605	0.116	0.475	0.736
miR-1228-3p + miR-133a-3p + miR-545-3p; + miR-181a-5p	0.614	0.089	0.491	0.737
miR-1228-3p + miR-133a-3p + miR-545-3p; + miR-361-5p	0.640	0.037	0.516	0.764
miR-1228-3p + miR-133a-3p + miR-181a-5p; + miR-361-5p	0.663	0.015	0.538	0.789
miR-1228-3p + miR-545-3p + miR-181a-5p; + miR-361-5p	0.607	0.112	0.477	0.737
miR-133a-3p + miR-545-3p + miR-181a-5p; + miR-361-5p	0.623	0.067	0.493	0.753
miR-1228-3p + miR-133a-3p + miR-545-3p; + miR-181a-5p + miR-361-5p	0.623	0.067	0.493	0.753

Note: P <0.05, P <0.01.