Phosphatidylinositol-4,5-Biphosphate (PI(4,5)P₂) Is Required for Rapid Endocytosis in Chromaffin Cells

Figure 1

Stimulation protocol consisting of a train of 10 depolarizations, from a holding potential of −80 mV to +10 mV, each lasting 50 ms; 500 ms separated each depolarization; Each depolarization was preceded by a 50 ms prepulse to +120 mV to recruit facilitation Ca²⁺ channels [7, 8].