Research Article

Altered Long Noncoding RNA Expression Profile in Multiple Myeloma Patients with Bisphosphonate-Induced Osteonecrosis of the Jaw

Table 1

Number of controls and patients and clinical features of the examined disease.

GroupNo. of patients (males, females)Age (years)Area with BONJBP treatment (yes/no (duration))Durie–Salmon disease stage (no. of patients)Median plasmocytosis (range)Ig class

CTRL8 (4 M, 4 F)N/ANoN/AN/AN/A
MM8 (5 M, 3 F)N/AYes (>1 year)II (5)
III (3)
65% (51–89%)IgG
BONJ8 (3 M, 5 F)Mandible (5 patients)
Maxilla (3 patients)
Yes (>1 year)II (4)
III (4)
74% (56–95%)IgG

CTRL: control group; MM: multiple myeloma patients without bisphosphonate-induced osteonecrosis of the jaw; MM+BONJ: multiple myeloma patients with bisphosphonate-induced osteonecrosis of the jaw; BP: bisphosphonates.