Research Article

Importance of KIM-1 and MCP-1 in Determining the Leptospirosis-Associated AKI: A Sri Lankan Study

Table 3

Serum and urine KIM-1 and MCP-1 concentration (ng/ml) stratified by AKI status.

Renal biomarker [median, (IQR) (range)]All cases ()Leptospirosis-confirmed patients ()Leptospirosis-unconfirmed patients ()
AKI ()Non-AKI () valueAKI ()Non-AKI () valueAKI ()Non-AKI () value

KIM-1
 Serum115.37 (306.78) (10.75-1571.18)21.80 (48.89) (1.18-1161.02)<0.0001143.80 (283.17) (40.18-1571.18)37.77 (67.43) (2.51-493.48)<0.000144.94 (149.83) (10.75-371.75)13.71 (31.47) (1.18-1161.02)0.0233
 Urine894.30 (1708.78) (21.50-3025.01)180.10 (922.48) (2.56-2729.61)0.00091497.00 (1771.52) (95.90-3025.01)463.60 (1088.34) (5.03-2713.26)0.0053156.00 (617.49) (21.50-1996.05)76.28 (392.40) (2.56-2729.61)0.4956
MCP-1
 Serum257.70 (632.33) (17.72-1496.48)110.00 (176.44) (7.19-2508.52)0.0053457.30 (676.81) (17.72-1496.48)120.90 (180.75) (7.19-1039.16)0.0080132.60 (224.78) (67.13-367.28)94.09 (155.62) (7.69-2508.52)0.6178
 Urine399.80 (933.42) (1.07-2514.43)143.00 (318.93) (1.10-5017.05)0.0063450.90 (912.35) (5.67-2514.43)133.30 (308.61) (1.19-2056.71)0.0019209.50 (534.10) (1.07-734.56)144.60 (336.81) (1.10-5017.05)0.9036

: Mann-Whitney test.