Research Article
Prophylactic Norepinephrine Infusion Reduces Postoperative Complications and Hospitalization Time in Elderly Patients Undergoing Posterior Lumbar Spinal Fusion
Table 5
In-hospital complications in 120 patients after lumbar fusion surgery.
| Category | Complication | Control group (); (%) | Norepinephrine group (); (%) | RR | 95% CI | value |
| Cardiac | | 26 (43.3) | 14 (23.3) | 1.857 | 1.080–3.194 | 0.033 | Acute myocardial infarction (all NSTEMI) | 3 | 1 | | | | Arrhythmia | 2 | 2 | | | | Congestive heart failure | 3 | 1 | | | | Transient BNP increase | 18 | 10 | | | | Thromboembolic | Pulmonary embolism | 3 (5) | 1 (1.7) | 3 | 0.321–28.031 | 0.619 | Neurological | | 8 (13.3) | 4 (6.7) | 2 | 0.636–6.289 | 0.362 | Peripheral neuropathy | 2 | 1 | | | | Delirium/agitation | 6 | 3 | | | | Infectious | | 9 (15) | 6 (10) | 1.5 | 0.569–3.953 | 0.582 | Urinary tract infection | 2 | 2 | | | | Wound infection | 4 | 2 | | | | Urosepsis | 0 | 0 | | | | Pyelonephritis | 3 | 2 | | | | Genitourinary | | 3 (5) | 1 (1.7) | 3 | 0.321–28.031 | 0.619 | Renal failure | 1 | 0 | | | | Transient increase of creatinine | 2 | 1 | | | | Pulmonary | | 17 (28.3) | 9 (15) | 1.889 | 0.915–3.898 | 0.12 | Pneumonia | 5 | 2 | | | | Pulmonary atelectasis | 6 | 4 | | | | Respiratory failure | 6 | 3 | | | | Blood loss | Anemia requiring postoperative transfusion | 12 (20) | 10 (16.7) | 1.2 | 0.562–2.564 | 0.814 | Complications | | 78 | 45 | | | | Patients with complications | | 24 (40) | 11 (18.3) | 2.182 | 1.177–4.045 | 0.015 | Patients with more than one complication | | 16 (26.7) | 7 (11.7) | 2.286 | 1.014–5.153 | 0.062 |
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NSTEMI: non-ST elevation myocardial infarction; BNP: brain natriuretic peptide.
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