Role of SNPs in the Biogenesis of Mature miRNAs

Figure 7

The enrichment of SNP-pre-miRNAs on SNP location in mature miRNAs. As shown in (a), mature miRNA which is associated with P5_5 site change or not is named P5_5-associated mature miRNA. SNP-pre-miRNA which site is abnormally processed is named iso-SNP-pre-miRNA. SNP-pre-miRNA which site is normally processed is named nor-SNP-pre-miRNA.

(a) Nucleotide position of P5_5-associated mature miRNA

(b) Nucleotide position of P5_3-associated mature miRNA

(c) Nucleotide position of P3_5-associated mature miRNA

(d) Nucleotide position of P3_3-associated mature miRNA