Enhanced Biofilm Eradication and Reduced Cytotoxicity of a Novel Polygalacturonic and Caprylic Acid Wound Ointment Compared with Common Antiseptic Ointments

Figure 2

In vitro cytotoxicity testing by Alamar blue metabolic activity assay. L-929 fibroblasts were treated with a 2% extract of 1% polygalacturonic acid+0.4% caprylic acid (PG-CAP), MediHoney, BZK, or PHMB. Nonantimicrobial ointment base and untreated cells were used as controls. Results are expressed as a percentage of absorbance relative to control, as measured by a spectrophotometer at 570 nm. Higher activity indicates lower cytotoxicity.