PTHR1 Genetic Polymorphisms Are Associated with Osteoporosis among Postmenopausal Arab Women
Table 4
Comparative analysis of inflammatory marker levels according to PTHR1 rs1138518 genotypes in the study groups.
Parameters
PTHR1 rs1138518
values
values
CG
PMO
Genotype T/T
IL-4 (pg/ml)
5.4 (3.5-7.7)
3.8 (3.0-7.4)
0.44
0.51
IL-1β (pg/ml)
1.6 (0.3-2.7)
0.4 (0.3-1.6)
0.16
0.15
Leptin (pg/ml)
22697.3 (11742.5-42916.3)
28803.4 (12919.2-37878.6)
0.84
0.29
TGF-β (pg/ml)
40749.5 (37204.7-48681.4)
43097.6 (40137.4-51499.3)
0.62
0.55
Genotype C/T
IL-4 (pg/ml)
8.2 (4.2-10.6)
4.1 (2.5-9.0)
0.10
0.26
IL-1β (pg/ml)
1.8 (0.5-2.7)
2.0 (0.3-2.8)
0.69
0.93
Leptin (pg/ml)
14532.2 (4761.6-27012.4)
20484.0 (10396.4-29426.2)
0.14
0.27
TGF-β (pg/ml)
37710.2 (29447.5-52241.4)
34811.5 (17464.4-46481.6)
0.31
0.13
Genotype C/C
IL-4 (pg/ml)
7.1 (3.7-10.7)
4.6 (2.5-9.3)
0.6
0.06
IL-1β (pg/ml)
1.8 (0.4-2.9)
1.6 (0.3-2.7)
0.22
0.09
Leptin (pg/ml)
14405.6 (1020.8-33059.9)
18808.1 (3756.0-31273.4)
0.71
0.39
TGF-β (pg/ml)
42041.5 (26232.0-54136.5)
33770.1 (15509.4-50533.2)
0.08
0.09
Note: data presented as for normal variables while median (Q1–Q3) for nonnormal variables; considered significant. Adjusted value for adjustment for multiple comparisons.
