Review Article

Exploring the Operative Strategy for Secondary Mitral Regurgitation: A Systematic Review

Table 2

Outcomes of S-MVR surgery.

First author (ref. #)Number of patientsFollow-up (yrs)Type of surgeryMain findings

Goldstein et al. [2]2512MVRpl/RMA
125/126
Higher rate of MR recurrence in RMA
Lorusso et al. [39]4888MVRpl/RMA
244/244
Higher rate of MR recurrence in RMA
Magne et al. [20]37012MVRpl/RMA
184/185
Similar rate of MR recurrence
Micovic et al. [13]1387MVRpl/RMA
52/86
Better survival in RMA
Milano et al. [14]52212MVRpl/RMA
106/416
Lower rate of 30-day mortality in RMA
Silbermann et al. [15]523,2MVRpl/RMA
14/38
Similar rate of survival. Better improvement in NYHA for RMA
Thourani et al. [21]125010MVRpl/RMA
625/625
Better 30 days and 10 yrs survival in RMA
McGee et al. [18]5855RMAAfter 1 yrs 3+ or 4+ MV regurgitation increased ()
Yan et al. [12]361MVRpl-cp/MVRpl-pp
21/15
Significant early advantage with MV
Sparing procedure
Natsuaki et al. [16]2830 daysMVRpl-cp/MVRpl-pp/RMA
15/13/15
Significant early advantage with MV
Sparing procedure
Rozich et al. [22]157/10 daysMVRpl-cp/MVRpl-pp
8/7
MVRpl-cp smaller LV size and LV function
David et al. [11]1724 monthsMVRpl-cp/MVRpl-pp/RMA
6/6/5
Better improvement of LV function. Significant benefit in preservation of chordae attachment to leaflet and PMs

LV: left ventricle; MR: mitral regurgitation; MVRpl: mitral valve replacement; MVRpl-cp: mitral valve replacement complete preservation; MVRpl-pp: partial preservation; PMs: papillary muscles; RMA: restrictive mitral annuloplasty; S-MVR: secondary mitral valve regurgitation surgery. See text for other abbreviations.