Research Article

Genetic Mutation Analysis in Small Cell Lung Cancer by a Novel NGS-Based Targeted Resequencing Gene Panel and Relation with Clinical Features

Table 1

Clinical characteristics of SCLC patients.

ParametersClinical valuesStage IStages II + III value

Age (years old)65 (49, 81)67 (51, 81)63 (49, 81)0.2506
Sex (male/female)24/812/412/40.9999
CYFRA21-1 (ng/ml)4.94 (1.24, 19.53)3.41 (1.24, 19.53)3.07 (2.04, 4.43)0.5033
CEA (ng/ml)4.33 (0.83, 18.37)2.97 (0.83, 16.59)2.52 (1.37, 18.37)0.9786
NSE (ng/ml)14.37 (1.83, 34.00)10.74 (1.83, 20.26)15.60 (11.38, 34.00)
SCCA (ng/ml)0.97 (0.20, 3.08)0.88 (0.20, 1.83)0.86 (0.21, 3.08)0.9742

Reported are median and range, except for sex is total individuals. values for age, CYFRA21-1, CEA, NSE, and SCCA were generated by Wilcoxon rank sum test; value for sex was generated by Fisher’s exact test.